Presenter: Anne Shiu, PhD, Assistant Professor, Department of Mathematics, Texas A&M University
Title: Dynamics of phosphorylation systems
Abstract: Reaction networks taken with mass-action kinetics arise in many settings, from epidemiology to population biology to systems of chemical reactions.
This talk focuses on certain biological signaling networks, namely, phosphorylation networks, and their resulting dynamical systems. For many of these systems, the set of steady states admits a rational parametrization (that is, the set is the image of a map with rational-function coordinates). We describe how such a parametrization allows us to investigate the dynamics of phosphorylation networks, including the emergence of bistability in a network underlying ERK regulation, and the capacity for oscillations in a mixed processive/distributive phosphorylation network.
Time: 11:00 this morning to noon
Place: 195 Farmington Avenue, 3rd Floor Conference Room U3071 A/B
Host: Reinhard Laubenbacher, Ph.D.
For more information, contact: Jane Tran Sills at x4799