CICATS Seminar Series: A Kavli BRAIN Event
Friday, March 24
Low Learning Center
12:00 p.m. to 1:00 p.m.
Speaker: Elisabet Borsheim, Ph.D., from the Arkansas Children’s Nutrition Center and the University of Arkansas for Medical Sciences
Topic: “Muscle protein synthesis and breakdown; regulation by nutrients and exercise”
Dr. Borsheim will discuss how muscle plays an essential role as the primary reservoir for amino acids to maintain needs in vital organs during catabolic periods, including between meals and in response to injuries. Hence, the regulation of muscle protein metabolism for adequate metabolic function is of high importance in health and disease. Stable isotope methodology enables measurements of muscle protein synthesis and breakdown rates. Intake of amino acids, specifically essential amino acids, stimulates muscle protein synthesis, and improves the net balance between synthesis and breakdown. During aging, there is a loss of muscle mass and function (sarcopenia) that may partly be explained by anabolic resistance. Optimal nutritional intake and exercise is of importance for maintenance of muscle mass with aging. After burn injuries, whole body and muscle protein turnover are increased, with a net loss of muscle protein and thus muscle mass. Anabolic interventions after pediatric burn injuries can improve muscle protein net balance via various mechanisms, including improving the response to feeding.
Lunch will be provided for seminar attendees.
The UConn School of Medicine designates this live activity for a maximum of 1 AMA PRA Category 1 Credit(s)tm. Physicians should only claim the credit commensurate with the extent of their participation in the activity.
RSVP by March 17 to Cheryl Steciak at csteciak@uchc.edu.
This luncheon seminar is hosted by the Connecticut Institute for Clinical and Translational Science (CICATS) at UConn, the CICATS Biostatistics Center, and The Kavli Foundation.
For more information, contact: Cheryl Steciak at csteciak@uchc.edu