Seminar Title: “Impact of Target-Mediated Drug Disposition on Small-Molecule Drug Discovery and Development”
PBB 131
Wednesday April 1, 2026, from 3:30 pm – 4:30 pm
Guohua An, MD, PhD, currently is an Associate Professor in the Department of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy at the University of Iowa, USA. She holds MD from Taishan Medical College (2000, China), MS in Clinical Pharmacology from Fudan University (2003, China), and PhD in Pharmaceutical Sciences from SUNY, University at Buffalo (2010, USA). Prior to joining academia, she worked for two and half years at Abbott (currently known as AbbVie), where she gained extensive hands-on experience in clinical drug development, pharmacokinetics (PK)/pharmacodynamics (PD) modeling and simulation. Her research interests include mechanism-based PK/PD modeling of small-molecule compounds and protein drugs; model-informed drug development (MIDD); model-informed clinical care (MICC); population pharmacokinetic modeling of drugs in special populations; and quantitative systems pharmacology (QSP).
Dr. An has been in the PK/PD field for 20 years and has published 102 peer-reviewed articles. Dr. An is an editor of Journal of Pharmaceutical Sciences, and she serves as an editorial board member of Journal of Clinical Pharmacology, The AAPS Journal, and Journal of Pharmacokinetics and Pharmacodynamics. Courses she teaches include “Pharmacokinetics and Dose Optimization” (PharmD course; 2-credit; sole instructor) and “Advanced Pharmacokinetics and Pharmacodynamics” (graduate course; 3-credit; sole instructor).
In addition to pharmaceutical research and teaching, she loves art and writing. She has written the following single-author books (amazon.com/author/guohua-an):
PK textbooks:
- Essentials in Clinical Pharmacokinetics: Concepts, Dose Optimization, and Biologics (Released in May 2024)
- Advanced Pharmacokinetics and Pharmacodynamics: Lecture Notes and Self-study guide (released in May 2025)
Non-fiction books:
- Magic Bullets and Beyond: Stories Behind the Drugs that Changed the World Series, Book 1 (Released in June 2024)
- The Unforgettables: Stories Behind the Drugs that Changed the World Series, Book 2 (Released in Nov 2024)
Education & Training
Ph.D. SUNY, University at Buffalo, Buffalo, New York, United States
MS, Fudan University, Shanghai, China
For more information, contact: Reena Bokria at rjb07003@uconn.edu