Dylan Murray, Assistant Professor of Chemistry, University of California
"Molecular Assembly Mechanisms for Low Complexity Domain Proteins"
The role of intrinsically disordered protein domains with reduced amino acid complexity in RNA metabolism and the cell cytoskeleton will be discussed. Solid state NMR, electron microscopy, bright field imaging, and fluorescence spectroscopy measurements will be presented that reveal how these proteins assemble into macroscopic structures.
About Dr. Murray: A molecular biophysicist by training, Dylan Murray, helped develop magnetic resonance methods to study M. tuberculosis membrane protein drug targets as a graduate student at the Institute for Molecular Biophysics and the National High Magnetic Field Laboratory of Florida State University. After that, he moved to the Laboratory of Chemical Physics at the National Institutes of Health to study proteins responsible for the formation of RNA granules. Currently, Dylan leads a team of researchers at the University of California, Davis, focused on determining how the microscopic properties of biopolymers produce the diverse macroscopic structures observed in cells, and how changes in these properties relate to neurodegenerative disease and cancer. To learn more about Dr. Murray’s work, view his publication: https://pubs.acs.org/doi/10.1021/jacs.2c08596 and his website: https://murraylab.ucdavis.edu/
For more information, contact: Maggie McDonnell at maggie.mcdonnell@uconn.edu