Seminar title “The Role of Conformational Dynamics in USP7 Enzyme Activity”
Wednesday, October 7th, 2020, from 3:30 – 4:30 via WebEx Link:
https://uconn-cmr.webex.com/join/boc07001
Dr. Bezsonova is an Associate Professor, Department of Molecular Biology and Biophysics
Co-Director, Graduate Program in Molecular Biology and Biochemistry at UConn Health
The Bezsonova lab studies enzymes of ubiquitin pathway often dysregulated in cancer and neurodegenerative diseases to better understand molecular mechanism of their action and develop new therapies.
We integrate multiple structural biology tools such as NMR spectroscopy, X-ray crystallography and cryo-EM with other biophysical and biochemical methods to determine atomic resolution 3D structures of proteins, map their interactions with binding partners, and characterize their movement in solution.
Detailed knowledge of protein structure is used to develop new drugs suitable for anti-cancer therapies.
For more information, contact: Dr. Olga Vinogradova at 8604862972