Seminar Title: Dissecting Molecular Mechanisms of Transcription Regulation
Tuesday, April 2, 2019
3:30 - 4:30 pm
BPB 131
The Department of Molecular and Cell Biology welcomes Dr. John T. Lis, the Barbara McClintock Professor of Molecular Biology and Genetics at Cornell University, as part of the MCB Seminar Series.
John T. Lis is the Barbara McClintock Professor of Molecular Biology and Genetics at Cornell University. He did his undergraduate studies at Fairfield University and his graduate research at Brandeis University, receiving his Ph.D. in Biochemistry. His postdoctoral work focused on Drosophila gene regulation and chromosome structure at Stanford University, during which time he was supported by a fellowship from the Helen Hay Whitney Foundation. Dr. Lis joined the faculty at Cornell in 1978. His research program has been supported mainly by the National Institutes of Health, including a MERIT Award. Dr. Lis was elected to the National Academy of Arts & Sciences in 2013 and was inducted into the National Academy of Science in 2015.
The Lis Lab develops and uses a variety of strategies to investigate mechanisms of gene regulation in living cells. The Lis Lab has had a history of developing methodologies to provide new views of transcription regulation. In Dr. Lis’ first several years at Cornell, the lab developed UV-crosslinking methods to map protein-DNA interactions in vivo that served as the precursor for modern chromatin immunoprecipitation (ChIP) methods [1]. More recently, the lab developed several genome-wide assays, such as GRO-seq [2], PRO-seq [3], GRO-cap [4], and PRO-cap [3] for precisely mapping nascent RNAs and start sites, often with base pair precision. The Lab goals are to understand the molecular mechanics of genome transcription and its regulation
If you require accommodation for this event please contact the MCB Department in Advance: 860-486-4329
For more information, contact: leighton.core at leighton.core@uconn.edu